Introduction
The nervous system is the essential parts of the body. It is
classified as the central and peripheral systems. Where the CNS operates
between brain and spinal cord, the PNS extends from the spinal cord and other
parts of the body to induce sensory and motor impulses.
Any harm to the roots or nerve extensions, any external
injuries or any entrapment within the soft tissues leads to disruption of
entire system and production of various signs and symptoms. Peripheral neuropathic pain is the most dominant sign followed by a peculiar ‘pins and
needles’ kind of sensation and burning of feet, hands, fingers and toes.
What is the effect of
chemotherapy drugs on the peripheral nerves?
Chemotherapy medicines like interferon, thalidomide,
cisplatin, Paclitaxel etc are known to cause harm to the nerve structures, the
trunks and the branches. History of neuropathy and any previous chemotherapy
sessions are secondary factors for nerve damage. Present history of diabetes,
excessive alcohol intake, and tobacco or mal nutrition also makes the person
more prone to nerve problems.
What are the target
areas of neuropathies?
With repeated chemotherapy sessions and increasing amounts
of drug administered produces neuropathy symptoms at a higher side. These
symptoms are found most in the fingers and toes just like glove and stocking,
bowel irritation or blockage and pain over face, low back and chest.
Steps to minimize
side effects of chemotherapy
- Be aware of any signs of discomfort or abnormal feeling.
- Report of any sensory trouble.
- Read up all data given to you and follow necessary instructions.
- Make sure to follow post therapy care.
- Be prompt in decision making when it is related to treatment Vs quality of life.
Tips for self
protection
Avoid exposure to cold weather or ice, utmost care should be
taken while gardening or washing dishes, glass handling etc to avoid cuts or
abrasions. Wearing of gloves is helpful and thick socks with soft shoes are
good for people struggling with foot discomfort.
While cooking, make use of more pot holders or utensils with
long holders, and make use of assistive devices like stick or walker to avoid
falling down. Most importantly, a time to time inspection of skin is necessary
to look for cuts, burns or lesions etc.
How to seek
neuropathy pain relief?
Flexible splints are good for protecting the affected areas.
Participate more in active exercises, take a body massage for relaxation, and
take laxatives if constipation troubles you often. Nerve vitamins like B1, B6,
B12, E and niacin help to nourish the nerve while regular medications like
steroids or patches can be continued.
Post chemotherapy
management for neuropathy
Analgesics, anti depressants and anti convulsants are the
most important treatments for peripheral neuropathy. Active and resistive
exercises train the weak muscles and the patient is explained about the modifications
in his every day routine like daily chores, use of braces or walking aids. TENS
and biofeedback are safe and therapeutic modalities which provide pain relief
to a great extent.
